Conformational Clamping by a Membrane Ligand Activates the EphA2 Receptor
Justin M. Westerfield, Amita R. Sahoo, Daiane S. Alves, Brayan Grau, Alayna Cameron, Mikayla Maxwell, Jennifer A. Schuster, Paulo C. T. Souza, Ismael Mingarro, Matthias Buck, Francisco N. Barrera
Topics & Concepts
Transmembrane domainPeptideBiophysicsEPH receptor A2ChemistryReceptorTransmembrane proteinAllosteric regulationLigand (biochemistry)DimerBiochemistryBiologyReceptor tyrosine kinaseOrganic chemistryAxon Guidance and Neuronal SignalingNeuroscience and Neuropharmacology ResearchZebrafish Biomedical Research Applications