Effect of size on expression of bistability in mouse spinal motoneurons
Ronald M. Harris‐Warrick, Émilie Pecchi, Benoît Drouillas, Frédéric Brocard, Rémi Bos
Abstract
Bistability is not a common feature of all mouse spinal motoneurons. It is absent in small, slow motoneurons but present in most large, fast motoneurons. This difference results from differential expression of ionic currents that enable bistability, which are highly expressed in large motoneurons but small or absent in small motoneurons. These results support a possible role for fast motoneurons in maintenance of tonic posture in addition to their known roles in fast movements.
Topics & Concepts
NeuroscienceBistabilityBiologyExpression (computer science)Spinal cordChemistryCell biologyCommunicationPhysicsPsychologyComputer scienceOptoelectronicsProgramming languageMuscle activation and electromyography studiesIon channel regulation and functionZebrafish Biomedical Research Applications