Enhanced solubility, permeability, and tabletability of nicorandil by salt and cocrystal formation
M. K. Chaitanya Mannava, Anilkumar Gunnam, Anurag Lodagekar, Nalini R. Shastri, Ashwini Nangia, K. Anand Solomon
Abstract
Cocrystallization is a rational selection crystal engineering approach for the development of novel solid forms with enhanced physicochemical and mechanical properties.
Topics & Concepts
CocrystalSolubilityNicorandilSalt (chemistry)Crystal engineeringMaterials scienceChemical engineeringPermeability (electromagnetism)Rational designChemistryOrganic chemistryHydrogen bondNanotechnologyEngineeringMoleculeBiochemistryAnesthesiaMedicineMembraneCrystallography and molecular interactionsCrystallization and Solubility StudiesEnergetic Materials and Combustion