Inhibition of Cytochrome P450 Enzymes by Drugs-Molecular Basis and Practical Applications
F. Peter Guengerich
Abstract
experiments, it is possible to stratify clinical drug-drug interaction studies. A better understanding of drug interactions and training of physicians and pharmacists has developed. Finally, some P450s have been the targets of drugs in some cancers and other disease states.
Topics & Concepts
Cytochrome P450DrugPharmacologyComputational biologyEnzymeComputer scienceMedicineChemistryBiologyBiochemistryPharmacogenetics and Drug MetabolismComputational Drug Discovery MethodsCancer Treatment and Pharmacology