Pathophysiological implications of ventriculoarterial coupling in septic shock

Abstract

Take-home messageProper ventriculo-arterial coupling results in optimal cardiac output, adequate peripheral organ perfusion, and efficient circulation.The relation between stroke volume and the developed arterial pressure defined by the relative elastances of the left ventricle and arterial circuit reflect ventriculo-arterial coupling.Decoupling of either or both commonly occur in sepsis and are associated with inefficient LV ejection that can lead to LV failure.Ventriculo-arterial decoupling in sepsis can lead to decreased effectiveness of cardiovascular treatments.

Topics & Concepts