Maternal and Fetal Outcomes among Pregnant Women with Diabetes
M Gojnić, Jovana Todorović, Dejana Stanisavljević, Aleksandra Jotić, Ljiljana Lukić, Tanja Miličić, Nebojša Lalić, Katarina Lalić, Milica Stoiljković, Tamara Stanisavljević, Aleksandar Stefanović, Katarina Jeremić, Svetlana Vrzić-Petronijević, M. Petronijević, Zorica Terzić-Šupić, Maja Macura, Milan Perović, Sandra Babić, Pavle Piperac, Marija Jovanovic, Bijana Parapid, Krisitna Doklestic, Radmila Cerovic, Siniša Djurašević, Stefan Dugalić
Abstract
The aim of this study was to examine the differences in pregnancy complications, delivery characteristics, and neonatal outcomes between women with type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM), and gestational diabetes mellitus (GDM). This study included all pregnant women with diabetes in pregnancy in Belgrade, Serbia, between 2010 and 2020. The total sample consisted of 6737 patients. In total, 1318 (19.6%) patients had T1DM, 138 (2.0%) had T2DM, and 5281 patients (78.4%) had GDM. Multivariate logistic regression with the type of diabetes as an outcome variable showed that patients with T1DM had a lower likelihood of vaginal delivery (OR: 0.73, 95% CI: 0.64-0.83), gestational hypertension (OR: 0.47, 95% CI: 0.36-0.62), higher likelihood of chronic hypertension (OR: 1.88, 95% CI: 1.55-2.29),and a higher likelihood ofgestational age at delivery before 37 weeks (OR: 1.38, 95% CI: 1.18-1.63) compared to women with GDM. Multivariate logistic regression showed that patients with T2DM had a lower likelihood ofgestational hypertension compared to women with GDM (OR: 0.37, 95% CI: 0.15-0.92).Our results indicate that the highest percentage of diabetes in pregnancy is GDM, and the existence of differences in pregnancy complications, childbirth characteristics, and neonatal outcomes are predominantly between women with GDM and women with T1DM.