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Accurate detection of mosaic variants in sequencing data without matched controls

Yanmei Dou, Minseok Kwon, Rachel E. Rodin, Isidro Cortés‐Ciriano, Ryan N. Doan, Lovelace J. Luquette, Alon Galor, Craig L. Bohrson, Christopher A. Walsh, Peter J. Park

2020Nature Biotechnology93 citationsDOIOpen Access PDF

Topics & Concepts

IndelBiologyGeneticsMosaicComputational biologyDNA sequencingDeep sequencingMutationGenomeHuman genomeSingle-nucleotide polymorphismGeneGenotypeHistoryArchaeologyCancer Genomics and DiagnosticsSingle-cell and spatial transcriptomicsGenomics and Rare Diseases
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