Electrochemical-induced solvent-tuned selective C(sp<sup>3</sup>)–H bond activation towards the synthesis of C3-functionalized chromone derivatives
Ying Gao, Mingxu Wang, Jingxian Sun, Xiaojing Zhao, Yonghui He
Abstract
)-H bond activation towards the synthesis of C3 functionalized chromone derivatives has been developed. This electrosynthesis protocol provides an efficient and green way to access various C3-functionalized chromones by avoiding traditionally employed transition metals and high temperatures. The swappable chemoselectivity was controlled mainly by altering the solvent and the current. A plausible reaction mechanism has been proposed with the help of radical capture and cyclic voltammetry experiments.
Topics & Concepts
ElectrosynthesisChromoneChemistryChemoselectivityElectrochemistryCyclic voltammetrySolventCombinatorial chemistryPhotochemistryCatalysisOrganic chemistryElectrodePhysical chemistryRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques