Volatile toxin of<i>Limonia acidissima</i>(L.) produced larvicidal, developmental, repellent, and adulticidal toxicity effects on<i>Aedes aegypti</i>(L.)
Muthiah Chellappandian, Sengottayan Senthil‐Nathan, Prabhakaran Vasantha‐Srinivasan, Sengodan Karthi, Kandaswamy Kalaivani, Wayne B. Hunter, Hayssam M. Ali, Mohamed Z. M. Salem, Ahmed Abdel‐Megeed
Abstract
The acute toxicity from volatile toxin from the Limonia acidissima (La-VO) was evaluated on the mosquito, Aedes aegypti. Screening of La-VO showed five major bioactive compounds with a major peak estragole. The mortality rate was significantly greater at 150 ppm La-VO. The lethal concentration (LC50) was observed at 65.24 ppm. Sub-lethal dosage of La-VO resulted in significant changes in developmental times. Enzymatic profile of larvae post treatment showed upregulation of CYP450 and GST levels. A maximum repellent activity was observed at 75 ppm La-VO at 98% up to 210 minutes. The La-VO provided evidence of insecticidal and toxicity to the mosquito.