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PAM-free cascaded strand displacement coupled with CRISPR-Cas12a for amplified electrochemical detection of SARS-CoV-2 RNA

Kai Shi, Zhigang Yi, Han Yao-xia, Jiaxuan Chen, Yu Hu, Ying Cheng, Sujun Liu, Wei Wang, Jiuhua Song

2023Analytical Biochemistry26 citationsDOIOpen Access PDF

Topics & Concepts

CRISPRRNAGuide RNABiosensorComputational biologyChemistryDNANucleic acidCas9Trans-activating crRNAMolecular biologyGeneBiologyBiochemistryAdvanced biosensing and bioanalysis techniquesCRISPR and Genetic EngineeringSARS-CoV-2 and COVID-19 Research
PAM-free cascaded strand displacement coupled with CRISPR-Cas12a for amplified electrochemical detection of SARS-CoV-2 RNA | Litcius