Pulmonary toxicity and gene expression changes in response to whole-body inhalation exposure to multi-walled carbon nanotubes in rats
Tina M. Sager, Christina Umbright, Mustafa Gül, Jenny R. Roberts, Marlene S. Orandle, Jared L. Cumpston, Walter McKinney, Theresa Boots, Michael L. Kashon, Pius Joseph
Abstract
Taken together, the data provided insights into the molecular mechanisms underlying the pulmonary toxicity induced by inhalation exposure of rats to MWCNT-7.
Topics & Concepts
Pulmonary toxicityToxicityBronchoalveolar lavageGene expressionInhalation exposureLactate dehydrogenaseInhalationChemistryInflammationLungImmunologyBiologyGeneMedicineInternal medicineBiochemistryEnzymeAnatomyOrganic chemistryAir Quality and Health ImpactsBiomarkers in Disease MechanismsNanoparticles: synthesis and applications