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Single-cell RNA-seq reveals characteristics in tumor microenvironment of PDAC with MSI-H following neoadjuvant chemotherapy with anti-PD-1 therapy

Kai Chen, Yongsu Ma, Xinxin Liu, Xiejian Zhong, Long Di, Xiaodong Tian, Lei Zheng, Yinmo Yang

2023Cancer Letters23 citationsDOI

Topics & Concepts

Tumor microenvironmentCancer researchGemcitabineImmunotherapyChemotherapyImmune checkpointBiologyMicrosatellite instabilityPembrolizumabOncologyInternal medicineImmune systemMedicineImmunologyGeneTumor cellsMicrosatelliteAlleleBiochemistryPancreatic and Hepatic Oncology ResearchCancer Genomics and DiagnosticsSingle-cell and spatial transcriptomics
Single-cell RNA-seq reveals characteristics in tumor microenvironment of PDAC with MSI-H following neoadjuvant chemotherapy with anti-PD-1 therapy | Litcius