Hydration of Aliphatic Nitriles Catalyzed by an Osmium Polyhydride: Evidence for an Alternative Mechanism
Juan C. Babón, Miguel A. Esteruelas, Ana M. López, Enrique Oñate
Abstract
-amidate ligand fixes the water molecule in the vicinity of the C(sp) atom of the nitrile.
Topics & Concepts
ChemistryNitrileAmideOsmiumCatalysisMoleculeMedicinal chemistryLigand (biochemistry)ChelationStereochemistryRutheniumOrganic chemistryBiochemistryReceptorAsymmetric Hydrogenation and CatalysisChemical Synthesis and AnalysisChemical Synthesis and Reactions