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A Predictive Model for Identifying the Most Effective Anti-CCR5 Monoclonal Antibody

Tatiana Hillman

2023Archives of Pharmacy Practice8 citationsDOIOpen Access PDF

Abstract

CCR5 (R5) inhibition is increasingly being studied for its potential to prevent, treat, and cure illnesses. R5 is a transmembrane protein that interacts with the CD4 receptor and CXCR4 (X4) of T cells, allowing the attachment of HIV viruses to lymphocytes. Consequently, because R5 inhibition has performed well as a medicinal drug, such as maraviroc, many researchers have speculated that R5 inhibition via binding antibodies may effectively treat HIV patients. However, currently, there is a lack o

Topics & Concepts

Monoclonal antibodyAntibodyMedicineImmunologyHIV Research and TreatmentMonoclonal and Polyclonal Antibodies Researchvaccines and immunoinformatics approaches
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