A Predictive Model for Identifying the Most Effective Anti-CCR5 Monoclonal Antibody
Tatiana Hillman
Abstract
CCR5 (R5) inhibition is increasingly being studied for its potential to prevent, treat, and cure illnesses. R5 is a transmembrane protein that interacts with the CD4 receptor and CXCR4 (X4) of T cells, allowing the attachment of HIV viruses to lymphocytes. Consequently, because R5 inhibition has performed well as a medicinal drug, such as maraviroc, many researchers have speculated that R5 inhibition via binding antibodies may effectively treat HIV patients. However, currently, there is a lack o
Topics & Concepts
Monoclonal antibodyAntibodyMedicineImmunologyHIV Research and TreatmentMonoclonal and Polyclonal Antibodies Researchvaccines and immunoinformatics approaches