Multiple epitope-based vaccine prediction against SARS-CoV-2 spike glycoprotein
Preeti Rana Sirohi, Jyoti Gupta, Pallavi Somvanshi, Vijay Kumar Prajapati, Abhinav Grover
Abstract
experiments indicate the potency of this vaccine candidate as a probable therapeutic agent against COVID-19. Vaccination strategies targeting conserved epitope-based immune response would be beneficial in providing cross protection across beta-coronaviruses, and such vaccines would be resistant to the ever-evolving viruses.Communicated by Ramaswamy H. Sarma.
Topics & Concepts
EpitopeComputational biologyIn silicoBiologyDocking (animal)AdjuvantPeptide vaccineEpitope mappingImmune systemVirologyCoronavirusVaccine efficacyAntibodyVaccinationImmunologyInfectious disease (medical specialty)Coronavirus disease 2019 (COVID-19)GeneticsMedicineDiseasePathologyNursingGenevaccines and immunoinformatics approachesSARS-CoV-2 and COVID-19 ResearchMonoclonal and Polyclonal Antibodies Research