Humanin attenuates palmitate-induced hepatic lipid accumulation and insulin resistance via AMPK-mediated suppression of the mTOR pathway
Chang-Hyuk Kwon, Jaw Long Sun, Ji Hoon Jeong, Tae Woo Jung
Topics & Concepts
AMPKInsulin resistanceLipogenesisPI3K/AKT/mTOR pathwayInternal medicineChemistryEndocrinologySterol regulatory element-binding proteinPhosphorylationFatty liverProtein kinase BSignal transductionLipid metabolismInsulinBiologyProtein kinase AMedicineBiochemistryCholesterolSterolDiseaseGDF15 and Related BiomarkersMetabolism, Diabetes, and CancerLiver Disease Diagnosis and Treatment