Recent development of gold(<scp>i</scp>) and gold(<scp>iii</scp>) complexes as therapeutic agents for cancer diseases
Yunlong Lu, Xiaoyan Ma, Xingyu Chang, Zhenlin Liang, Lin Lv, Min Shan, Qiuyue Lu, Zhenfan Wen, Ronald Gust, Wukun Liu
Abstract
reactive oxygen species (ROS). Interestingly, gold complexes were recently reported to elicit biochemical hallmarks of immunogenic cell death (ICD) as an ICD inducer. In this review, the recent progress of gold(I) and gold(III) complexes is comprehensively summarized, and their activities and mechanism of action are documented.
Topics & Concepts
CancerChemistryNanotechnologyCombinatorial chemistryMaterials scienceMedicineInternal medicineMetal complexes synthesis and propertiesFerrocene Chemistry and ApplicationsClick Chemistry and Applications