A supramolecular adduct of tegafur and syringic acid: the first tegafur-nutraceutical cocrystal with perfected <i>in vitro</i> and <i>in vivo</i> characteristics as well as synergized anticancer activities
Yue‐Ming Yu, Mingchao Yu, Ling‐Yang Wang, Yan‐Tuan Li, Zhi‐Yong Wu, Cui‐Wei Yan
Abstract
The <italic>in vitro</italic> and <italic>in vivo</italic> properties as well as synergistic antitumor activities of the first tegafur-nutraceutical cocrystal are reported.
Topics & Concepts
ChemistryCocrystalIn vivoNutraceuticalIn vitroTegafurPharmacologyCombinatorial chemistryBiochemistryOrganic chemistryCancerInternal medicineMoleculeBiotechnologyBiologyHydrogen bondMedicineCrystallography and molecular interactionsEnzyme Structure and FunctionCrystal structures of chemical compounds