Evidence that TNF-β suppresses osteoblast differentiation of mesenchymal stem cells and resveratrol reverses it through modulation of NF-κB, Sirt1 and Runx2
Constanze Buhrmann, Bastian Popper, Bharat B. Aggarwal, Mehdi Shakibaei
Topics & Concepts
RUNX2ResveratrolMesenchymal stem cellDownregulation and upregulationChemistryOsteoblastCell biologyTumor necrosis factor alphaSirtuin 1NF-κBCancer researchSignal transductionBiologyEndocrinologyBiochemistryIn vitroGeneMesenchymal stem cell researchBone and Joint DiseasesBone Metabolism and Diseases