Efficiency Improvements and Discovery of New Substrates for a SARS-CoV-2 Main Protease FRET Assay
Tonko Dražić, Nikos Kühl, Mila M. Leuthold, Mira A. M. Behnam, Christian D. Klein
Topics & Concepts
Förster resonance energy transferProteaseCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Substrate (aquarium)Chemistry2019-20 coronavirus outbreakCombinatorial chemistryComputational biologyVirologyEnzymeBiochemistryBiologyMedicineFluorescencePhysicsPathologyQuantum mechanicsEcologyInfectious disease (medical specialty)DiseaseOutbreakComputational Drug Discovery MethodsSARS-CoV-2 and COVID-19 ResearchLipid Membrane Structure and Behavior