Farnesoid X receptor (FXR) agonists induce hepatocellular apoptosis and impair hepatic functions via FXR/SHP pathway
Tianwei Zhang, Shanshan Feng, Jiahuan Li, Zhitao Wu, Qiangqiang Deng, Wei Yang, Jing Li, Guoyu Pan, Jing Li, Guoyu Pan
Topics & Concepts
Farnesoid X receptorObeticholic acidAgonistNuclear receptorHepatocyteInternal medicineChemistryLiver regenerationHepatic stellate cellEndocrinologyPharmacologyBiologyCancer researchCell biologyReceptorRegeneration (biology)MedicineBiochemistryTranscription factorGeneIn vitroDrug Transport and Resistance MechanismsLiver Disease Diagnosis and TreatmentLiver physiology and pathology