Synthesis, in vitro evaluation and molecular docking studies of hybrid 4-quinolinyl bearing 1,3,4-thiadiazole-2-amine as a new inhibitor of α-amylase and α-glucosidase
Muhammad Taha, Aftab Ahmad Khan, Fazal Rahim, Shawkat Hayat, Syahrul Imran, Naveed Iqbal, Nizam Uddin, Khalid Mohammed Khan, El Hassane Anouar, Rai Khalid Farooq, Muhammad Nawaz, Syed Adnan Alı Shah
Topics & Concepts
ChemistryIC50Docking (animal)EnzymeStereochemistryIn silicoAmylaseAmine gas treatingActive siteMolecular modelIn vitroBiochemistryOrganic chemistryMedicineNursingGeneSynthesis and biological activityNatural Antidiabetic Agents StudiesSynthesis and Characterization of Heterocyclic Compounds