Litcius/Paper detail

A challenging complication following SARS-CoV-2 infection: a case of pulmonary mucormycosis

Daniela Pasero, Silvana Sanna, Corrado Liperi, Davide Piredda, Gian Pietro Branca, Lorenzo Casadio, Raffaella Simeo, Alice Buselli, Davide Rizzo, Francesco Bussu, Salvatore Rubino, Pierpaolo Terragni

2020Infection186 citationsDOIOpen Access PDF

Abstract

Severe acute respiratory syndrome coronavirus 2 infection might induce a significant and sustained lymphopenia, increasing the risk of developing opportunistic infections. Mucormycosis is a rare but severe invasive fungal infection, mainly described in immunocompromised patients. The first case of a patient diagnosed with coronavirus disease (COVID-19) who developed a pulmonary mucormycosis with extensive cavitary lesions is here reported. This case highlights how this new coronavirus might impair the immune response, exposing patients to higher risk of developing opportunistic infections and leading to worse outcomes.

Topics & Concepts

MucormycosisOpportunistic infectionMedicineCoronavirusComplicationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Intensive care medicineDiseaseImmunologyInfectious disease (medical specialty)Viral diseaseInternal medicineHuman immunodeficiency virus (HIV)SurgeryAntifungal resistance and susceptibilityFungal Infections and Studies