Cyclization strategy leads to highly potent Bromodomain and extra-terminal (BET) Bromodomain inhibitors for the treatment of acute liver injury
Chao Chen, Tian Lu, Panyu Chen, Zizhou Li, Yaxi Yang, Shijie Fan, Yuanyuan Zhang, Kaixian Chen, Wei Fu, Yugang Wang, Cheng Luo, Bing Zhou
Topics & Concepts
BromodomainChemistryLiver injuryPharmacologyIn vitroCancer researchMedicineBiochemistryEpigeneticsGeneProtein Degradation and InhibitorsMultiple Myeloma Research and TreatmentsHIV Research and Treatment