Antidepressant-like effect of guanosine involves activation of AMPA receptor and BDNF/TrkB signaling
Priscila B. Rosa, Luis E.B. Bettio, Vivian B. Neis, Morgana Moretti, Fernanda Neutzling Kaufmann, Mauren K. Tavares, Isabel Werle, Yasmim de Oliveira Dalsenter, Nicolle Platt, Axel Fogaça Rosado, Daiane B. Fraga, Isabella A. Heinrich, Andiara E. Freitas, Rodrigo Bainy Leal, Ana Lúcia S. Rodrigues
Topics & Concepts
AMPA receptorTropomyosin receptor kinase BGuanosineTail suspension testChemistryEndocrinologyInternal medicineBrain-derived neurotrophic factorDentate gyrusPharmacologyBehavioural despair testHippocampal formationNeurotrophic factorsHippocampusAntidepressantMedicineReceptorGlutamate receptorBiochemistryGenetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology ResearchBipolar Disorder and Treatment