Spindle-like MRI-active europium-doped iron oxide nanoparticles with shape-induced cytotoxicity from simple and facile ferrihydrite crystallization procedure
A.V. Lunin, Ilya L. Sokolov, Ivan V. Zelepukin, Ilya Zubarev, Maria N. Yakovtseva, Elizaveta N. Mochalova, Julian M. Rozenberg, Maxim P. Nikitin, Eugene L. Kolychev
Abstract
Eu biodistribution measurements, these particles accumulate in the liver and spleen. Therefore, NPs present a novel example of a multimodal component combining magnetic imaging and therapeutic (cytotoxic) abilities for development of theranostic nanoagents.
Topics & Concepts
FerrihydriteEuropiumCrystallizationNanoparticleDopingIron oxide nanoparticlesIron oxideSimple (philosophy)CytotoxicityMaterials scienceOxideChemistryChemical engineeringNuclear chemistryInorganic chemistryNanotechnologyOrganic chemistryLuminescenceBiochemistryOptoelectronicsAdsorptionEpistemologyEngineeringPhilosophyIn vitroIron oxide chemistry and applicationsNanoparticle-Based Drug DeliveryIron Metabolism and Disorders