Dysregulation of the Gut Microbiota Contributes to Sevoflurane-Induced Cognitive Dysfunction in Aged Mice by Activating the NLRP3 Inflammasome
Shanshan Han, Ruxi Bian, Yuxuan Chen, Junjie Liang, Peng Zhao, Yanfang Gu, Dengxin Zhang
Topics & Concepts
NeuroinflammationGut floraDysbiosisInflammasomeSevofluraneMedicinePostoperative cognitive dysfunctionAkkermansiaCognitive declineImmunologyInternal medicineCognitionAnesthesiaInflammationBiologyPsychiatryDiseaseDementiaBacteriaGeneticsBacteroidesIntensive Care Unit Cognitive DisordersAnesthesia and Neurotoxicity ResearchTryptophan and brain disorders