Celastrol attenuates 6-hydroxydopamine-induced neurotoxicity by regulating the miR-146a/PI3K/Akt/mTOR signaling pathways in differentiated rat pheochromocytoma cells
Liying Guo, Baoming Qu, Chengyuan Song, Shaowei Zhu, Nianming Gong, Jinhao Sun
Topics & Concepts
PI3K/AKT/mTOR pathwayNeurotoxicityProtein kinase BHydroxydopamineNeuroprotectionViability assayApoptosisChemistryCell biologyFlow cytometryPharmacologyMolecular biologyBiologyBiochemistryEndocrinologyToxicityDopamineOrganic chemistryDopaminergicNatural Compounds in Disease TreatmentNuclear Receptors and SignalingParkinson's Disease Mechanisms and Treatments