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<i>In vitro</i>and<i>In silico</i>anticancer activities of Mn(<scp>ii</scp>), Co(<scp>ii</scp>), and Ni(<scp>ii</scp>) complexes: synthesis, characterization, crystal structures, and DFT studies

M.K. Gond, Shivendra Kumar Pandey, Ranjeet Singh, M.K. Bharty, Partha Pratim Manna, Vinay Kumar Singh, Biswajit Maiti, L. B. Prasad, Ray J. Butcher

2022New Journal of Chemistry22 citationsDOI

Abstract

Complexes 1, 2 and 3 showed significant activity against K562, MCF-7, and DL cancer cell lines. Complexes 1–3 showed higher growth inhibition than metal salts or ligands in tumour cell growth and colony formation. Complex 1 exhibited higher anticancer activity than cisplatin.

Topics & Concepts

ChemistryIn vitroStereochemistryCisplatinBiochemistryChemotherapySurgeryMedicineMetal complexes synthesis and propertiesFerrocene Chemistry and ApplicationsMagnetism in coordination complexes
<i>In vitro</i>and<i>In silico</i>anticancer activities of Mn(<scp>ii</scp>), Co(<scp>ii</scp>), and Ni(<scp>ii</scp>) complexes: synthesis, characterization, crystal structures, and DFT studies | Litcius