Cationic palladium(<scp>ii</scp>)-indenyl complexes bearing phosphines as ancillary ligands: synthesis, and study of indenyl amination and anticancer activity
Enrica Bortolamiol, Francesco Fama, Ziyun Zhang, Nicola Demitri, Luigi Cavallo, Isabella Caligiuri, Flavio Rizzolio, Thomas Scattolin, Fabiano Visentin
Abstract
tests have proven that these organometallic compounds promote antiproliferative activity towards ovarian cancer cells better than cisplatin and possibly by adopting a different mechanism of action.
Topics & Concepts
ChemistryDenticityNucleophileAminationReactivity (psychology)PalladiumSteric effectsPhosphineLigand (biochemistry)Combinatorial chemistryCationic polymerizationAmine gas treatingElectronic effectStereochemistryMedicinal chemistryCatalysisOrganic chemistryMetalAlternative medicineReceptorMedicineBiochemistryPathologyCatalytic Cross-Coupling ReactionsAsymmetric Hydrogenation and CatalysisOrganometallic Complex Synthesis and Catalysis