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Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states

Yingyuan Sun, Xiaochun Li

2022Nature Cardiovascular Research38 citationsDOIOpen Access PDF

Topics & Concepts

ABCA1ATP Binding Cassette Transporter 1ATP-binding cassette transporterBiochemistryTangier diseaseCholesterolEffluxTransporterMutantTransmembrane proteinBiologyTransmembrane domainCell biologyReverse cholesterol transportBiophysicsChemistryLipoproteinAmino acidGeneReceptorCholesterol and Lipid MetabolismDrug Transport and Resistance MechanismsRNA and protein synthesis mechanisms
Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states | Litcius