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Cellular states are coupled to genomic and viral heterogeneity in HPV-related oropharyngeal carcinoma

Sidharth V. Puram, Michael Mints, Ananya Pal, Zongtai Qi, Ashley N. Reeb, Kyla Gelev, Thomas F. Barrett, Sophie P. Gerndt, Ping Liu, Anuraag S. Parikh, Salma Ramadan, Travis Law, Edmund A. Mroz, James W. Rocco, D.R. Adkins, Wade L. Thorstad, Hiram A. Gay, Li Ding, Randal C. Paniello, Patrik Pipkorn, Ryan S. Jackson, Xiaowei Wang, Angela L. Mazul, Rebecca D. Chernock, José P. Zevallos, Jessica Silva-Fisher, Itay Tirosh

2023Nature Genetics108 citationsDOIOpen Access PDF

Topics & Concepts

BiologyCancer researchPhenotypeHead and neck squamous-cell carcinomaGenome instabilityCell cycleCellGeneHuman papillomavirusCancerHead and neck cancerGeneticsDNA damageInternal medicineDNAMedicineCancer-related molecular mechanisms researchSingle-cell and spatial transcriptomicsRNA modifications and cancer
Cellular states are coupled to genomic and viral heterogeneity in HPV-related oropharyngeal carcinoma | Litcius