Unveiling the cyclopropyl appended acyl thiourea derivatives as antimicrobial, α-amylase and proteinase K inhibitors: Design, synthesis, biological evaluation, molecular docking, DFT and ADMET studies
H. Fahrul Zaman, Aamer Saeed, Hammad Ismail, Muhammad Rashid
Topics & Concepts
ThioureaDocking (animal)ChemistryAntimicrobialCombinatorial chemistryStereochemistryMolecular modelBiochemistryOrganic chemistryMedicineNursingClick Chemistry and ApplicationsCyclopropane Reaction MechanismsHIV/AIDS drug development and treatment