Litcius/Paper detail

Early-life risk factors for reversible and irreversible airflow limitation in young adults: findings from the BAMSE birth cohort

Gang Wang, Inger Kull, Anna Bergström, Jenny Hallberg, Petra Um‐Bergström, Stefano Guerra, Göran Pershagen, Olena Gruzieva, Marianne van Hage, Antonios Georgelis, Christer Janson, Anders Lindén, Erik Melén

2020Thorax30 citationsDOIOpen Access PDF

Abstract

We aimed to determine prevalence and early-life risk factors for reversible and irreversible airflow limitation in young adults from the general population. Among young adults in their 20s, the prevalence was 5.3% for reversible airflow limitation and 2.0% for irreversible airflow limitation. While parental asthma was the only risk factor for development of reversible airflow limitation, the risk factors for development of irreversible airflow limitation were current asthma, childhood respiratory tract infections and asthma, and exposure to air pollution.

Topics & Concepts

MedicineAirflowAsthmaRisk factorCohortRespiratory tractPopulationPediatricsCohort studyYoung adultRespiratory systemEnvironmental healthInternal medicineMechanical engineeringEngineeringAsthma and respiratory diseasesChronic Obstructive Pulmonary Disease (COPD) ResearchInhalation and Respiratory Drug Delivery