Alisol B 23-acetate adjusts bile acid metabolisim via hepatic FXR-BSEP signaling activation to alleviate atherosclerosis
Yu Fu, Han Feng, Xue Ding, Qinghai Meng, Shu-Rui Zhang, Jun Li, Ying Chao, Tingting Ji, Yunhui Bi, Weiwei Zhang, Qi Chen, Yuhan Zhang, Youlong Feng, Huimin Bian
Topics & Concepts
Farnesoid X receptorInternal medicineEndocrinologyCholesterol 7 alpha-hydroxylaseBile acidCholesterolCYP8B1ChemistryChenodeoxycholic acidOvariectomized ratG protein-coupled bile acid receptorSmall heterodimer partnerBiologyMedicineEstrogenBiochemistryNuclear receptorGeneTranscription factorCholesterol and Lipid MetabolismDrug Transport and Resistance MechanismsBerberine and alkaloids research