UK guidelines for the investigation and management of eosinophilia in returning travellers and migrants
Clare Thakker, Clare E Warrell, Jessica Barrett, Helen Booth, Peter L. Chiodini, Sylviane Defres, Jane Falconer, Nathan Jacobs, Jayne Jones, Jonathan Lambert, Clare Leong, Angela McBride, Elinor Moore, Tara Moshiri, Laura Nabarro, Geraldine O’Hara, Neil Stone, Clare van Halsema, Anna M. Checkley
Abstract
Literature reviews have been undertaken to update the evidence on the prevalence and causes of eosinophilia in these groups and on the treatment of relevant pathogens and clinical conditions. Diagnostic tests available to UK-based clinicians are summarised. Changes made to the guidelines include updates in the sections on the investigation and empirical treatment of asymptomatic eosinophilia and on the treatment of trichuriasis, lymphatic filariasis, onchocerciasis, hookworm, fascioliasis and taeniasis. Pathogens which are rarely encountered in UK practice have been removed from the guidelines and others added, including an expanded section on fungal infection. A section on off-license and rarely used drugs has been included.