Enhancement of Liposomal Plasmid DNA and siRNA Delivery by Itraconazole through Intracellular Cholesterol Accumulation
Ira Shrestha, Jong‐Soo Choi, Yun‐Ui Bae, Kyung‐Oh Doh
Topics & Concepts
BafilomycinTransfectionItraconazoleIntracellularLysosomeGene deliveryLiposomeChemistryEndosomeCytotoxicityPhospholipidosisCationic liposomePharmacologyBiochemistryBiologyPhospholipidIn vitroGeneMembraneMicrobiologyAutophagyAntifungalEnzymeApoptosisRNA Interference and Gene DeliveryToxin Mechanisms and ImmunotoxinsVirus-based gene therapy research