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Acquired tamoxifen resistance is surmounted by GW8510 through ribonucleotide reductase M2 downregulation-mediated autophagy induction

Zhennan Li, Yang Shu, Chen-Guo Chen, Xiaoqin Li, Meiyu Li, Xiaohui Zhao, Shui Wang, Jian Li

2020Biochemical and Biophysical Research Communications18 citationsDOI

Topics & Concepts

TamoxifenAutophagyDownregulation and upregulationBreast cancerCancer researchMedicineCancerOncologyInternal medicinePharmacologyBiologyApoptosisBiochemistryGeneMetal-Catalyzed Oxygenation MechanismsDrug Transport and Resistance MechanismsAutophagy in Disease and Therapy
Acquired tamoxifen resistance is surmounted by GW8510 through ribonucleotide reductase M2 downregulation-mediated autophagy induction | Litcius