Polymorphous Low-Grade Neuroepithelial Tumor of the Young as a Partially Calcified Intra-Axial Mass in an Adult
John C. Benson, Daniel D. Summerfield, Carrie M. Carr, Petrice M. Cogswell, Steven A. Messina, Jamie J. Van Gompel, Kirk M. Welker
Abstract
Polymorphous low-grade neuroepithelial tumors of the young (PLNTYs) are recently described CNS tumors. Classically, PLNTYs are epileptogenic and are a subtype of a heterogeneous group of low-grade neuroepithelial tumors that cause refractory epilepsy, such as angiocentric gliomas, oligodendrogliomas, gangliogliomas, and pleomorphic xanthoastrocytomas. Although they are a relatively new entity, a number of imaging and histologic characteristics of PLNTYs are already known. We present the imaging and pathologic findings of such a tumor as well as the surgical approach and clinical management.
Topics & Concepts
Neuroepithelial cellMedicineGangliogliomaPathologyRefractory (planetary science)OligodendrogliomaEpilepsyGliomaAstrocytomaCancer researchBiologyStem cellNeural stem cellGeneticsAstrobiologyPsychiatryGlioma Diagnosis and TreatmentEpilepsy research and treatmentFetal and Pediatric Neurological Disorders