Atractylenolide-I Attenuates MPTP/MPP+‑Mediated Oxidative Stress in Parkinson’s Disease Through SIRT1/PGC‑1α/Nrf2 Axis
Ya Gao, Shuyue Li, Shuming Zhang, Yidan Zhang, Jian Zhang, Yuan Zhao, Chang Cui, Xuan Gao, Ling Chen, Guofeng Yang
Topics & Concepts
MPTPSubstantia nigraOxidative stressPars compactaNeuroprotectionMalondialdehydeSuperoxide dismutaseChemistryPharmacologyAntioxidantDopaminergicParkinson's diseaseReactive oxygen speciesBiochemistryDopamineEndocrinologyInternal medicineBiologyMedicineDiseaseSirtuins and Resveratrol in MedicineParkinson's Disease Mechanisms and TreatmentsBiochemical and biochemical processes