4-Phenylbutyrate Mitigates the Motor Impairment and Dopaminergic Neuronal Death During Parkinson’s Disease Pathology via Targeting VDAC1 Mediated Mitochondrial Function and Astrocytes Activation
Shubhangini Tiwari, Parul Gupta, Abhishek Singh, Swati Chaturvedi, Muhammad Wahajuddin, Amit Mishra, Sarika Singh
Topics & Concepts
Substantia nigraNeuroprotectionPharmacologyPars compactaTyrosine hydroxylaseVDAC1MitochondrionParkinson's diseaseBiologyDopamineDopaminergicMPTPInternal medicineEndocrinologyCell biologyMedicineBiochemistryDiseaseEscherichia coliBacterial outer membraneGeneParkinson's Disease Mechanisms and TreatmentsNeurological diseases and metabolismAutophagy in Disease and Therapy