Local and large-scale beta oscillatory dysfunction in males with mild traumatic brain injury
Jing Zhang, Kristina Safar, Zahra Emami, George M. Ibrahim, Shannon E. Scratch, Leodante da Costa, Benjamin T. Dunkley
Abstract
Mild traumatic brain injury (mTBI) disrupts the dynamic repertoire of neural oscillations, but so far beta activity has not been studied. In mTBI, we found reductions in frontal beta and large-scale beta networks, indicative of thalamocortical dysconnectivity and disrupted information flow through cortico-basal ganglia-thalamic circuits. Relatively, connectivity more accurately classifies individual mTBI cases compared with regional power. We show the relevance of beta oscillations in mTBI and the reliability of these markers in classification.
Topics & Concepts
Traumatic brain injuryNeuroscienceMagnetoencephalographyPsychologyNeurophysiologyFunctional magnetic resonance imagingBETA (programming language)ConcussionPoison controlElectroencephalographyMedicineComputer scienceInjury preventionPsychiatryEnvironmental healthProgramming languageNeural dynamics and brain functionFunctional Brain Connectivity StudiesHeart Rate Variability and Autonomic Control