Design, synthesis, and evaluation of N-benzylpyrrolidine and 1,3,4-oxadiazole as multitargeted hybrids for the treatment of Alzheimer’s disease
Priyanka Kumari Choubey, Avanish Tripathi, Manish Tripathi, Ankit Seth, Sushant K. Shrivastava
Topics & Concepts
ChemistryAcetylcholinesteraseButyrylcholinesteraseAchéIn vivoNeuroprotectionPharmacologyIn silicoDocking (animal)Ex vivoMorris water navigation taskOxidative stressIn vitroBiochemistryEnzymeNeuroscienceHippocampusBiologyGeneBiotechnologyMedicineNursingCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsMedicinal Plants and Neuroprotection