Litcius/Paper detail

Association of Industry Sponsorship With Cancer Clinical Trial Accrual

Dario Pasalic, Chad Tang, Reshma Jagsi, Clifton D. Fuller, Albert C. Koong, Ethan B. Ludmir

2020JAMA Oncology20 citationsDOIOpen Access PDF

Abstract

Poor accrual is the leading cause of cancer clinical trial failure, most commonly affecting late-phase trials, but the factors associated with successful accrual remain poorly understood. [1] 2][3] We therefore sought to evaluate oncologic phase 3 trials using a mandatory web-based registration database as a means of identifying and quantifying factors associated with accrual completion.

Topics & Concepts

MedicineAccrualCancerClinical trialMEDLINEFamily medicineOncologyInternal medicineAccountingEarningsPolitical scienceBusinessLawPharmaceutical industry and healthcareBiomedical Ethics and RegulationPharmaceutical Economics and Policy