The Wnt/β-catenin signaling pathway plays a role in drug-induced liver injury by regulating cytochrome P450 2E1 expression
Yoo‐Sub Shin, Da‐Bin Hwang, Dong‐Hoon Won, Shin-Young Kim, Changuk Kim, Jun Won Park, Young Joo Jeon, Jun-Won Yun
Topics & Concepts
CYP2E1Wnt signaling pathwayLiver injuryAcetaminophenPharmacologyChemistryApoptosisCytochrome P450Signal transductionMedicineBiochemistryMetabolismDrug-Induced Hepatotoxicity and ProtectionLiver physiology and pathologyPharmacogenetics and Drug Metabolism