An optimized ionizable cationic lipid for brain tumor-targeted siRNA delivery and glioblastoma immunotherapy
Shuhan Liu, Ji Liu, Haisong Li, Kuirong Mao, Haorui Wang, Xiandi Meng, Jialiang Wang, Chenxi Wu, Hongmei Chen, Xin Wang, Xiuxiu Cong, Yue Hou, Ye Wang, Ming Wang, Yong‐Guang Yang, Tianmeng Sun
Topics & Concepts
Cancer researchImmunotherapyGene silencingBrain tumorDrug deliverySmall interfering RNAGlioblastomaGene deliveryEndosomeBlood–brain barrierRNA interferenceImmune systemGenetic enhancementDownregulation and upregulationMedicineCellChemistryImmunologyMaterials scienceTransfectionNanotechnologyPathologyCentral nervous systemGeneRNABiochemistryInternal medicineRNA Interference and Gene DeliveryImmunotherapy and Immune ResponsesNanoplatforms for cancer theranostics