Increased Notch2/NF-κB Signaling May Mediate the Depression Susceptibility: Evidence from Chronic Social Defeat Stress Mice and WKY Rats
Jiangfeng Liao, Guirong Zeng, Wenting Fang, Weibin Huang, Xiaoman Dai, Qinyong Ye, Jing Zhang, Xiaochun Chen
Topics & Concepts
HES1Social defeatPrefrontal cortexChronic stressDepression (economics)EndocrinologyDownregulation and upregulationInternal medicineNotch signaling pathwayPsychologyNeuroscienceMedicineBiologyReceptorGeneGeneticsEconomicsMacroeconomicsCognitionStress Responses and CortisolTryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms