Leveraging base excision repair for efficient adenine base editing of mitochondrial DNA
Yuhang Fan, Wenchao Xu, Bao‐Qing Gao, Hao Qin, Xiaoyi Wu, Jia Wei, Qingyang Ni, Lina Zhou, Jiangchao Xiang, Jing Wu, Bei Yang, Li Yang, Jia Chen
Topics & Concepts
Base excision repairMitochondrial DNABase (topology)Nucleotide excision repairDNABase pairDNA repairChemistryBiologyComputational biologyGeneticsGeneMathematicsMathematical analysisCRISPR and Genetic EngineeringMitochondrial Function and PathologyRNA and protein synthesis mechanisms