H-Phosphonate Chemistry in the Synthesis of Electrically Neutral and Charged Antiviral and Anticancer Pronucleotides
Adam Kraszewski, Michał Sobkowski, Jacek Stawiński
Abstract
In this review a short account of our work on the synthesis and biological activity of electrically neutral and charged anti-HIV and anticancer pronucleotides, presented on the background of the contemporary research in this area, is given.
Topics & Concepts
PhosphonateChemistryHuman immunodeficiency virus (HIV)NanotechnologyCombinatorial chemistryOrganic chemistryVirologyMaterials scienceMedicineHIV/AIDS drug development and treatmentDNA and Nucleic Acid ChemistryClick Chemistry and Applications