Pyrrolo[2,1-<i>a</i>]isoquinoline scaffolds for developing anti-cancer agents
Leidy J. García Maza, Arturo René Mendoza Salgado, Vladímir V. Kouznetsov, Carlos M. Meléndez
Abstract
]isoquinolines, exploring synthetic strategies in total synthesis and molecular diversification trends, highlighting their importance in the field of medicinal chemistry and beyond.
Topics & Concepts
IsoquinolineTopoisomeraseCytotoxic T cellChemistryCombinatorial chemistryStereochemistryCancerMoleculePharmacologyBiochemistryBiologyMedicineIn vitroOrganic chemistryInternal medicineSynthesis and Characterization of PyrrolesCatalytic C–H Functionalization MethodsCyclopropane Reaction Mechanisms